Surface-Bound Membrane-Mimetic Assemblies: Electrostatic Attributes of Integral Membrane Proteins
Abstract
This project aims to incorporate integral membrane proteins into matrices that mimic the natural lipid bilayer, but which are linked with electrically active solid surfaces. The structures are formed by adapting approaches that are commonly used to form model membrane vesicles in a manner that allows the membrane proteins and lipids to assemble into membrane structures on a surface. The objective is to use these structures to investigate stimulus-induced displacements of charges associated with membrane receptor proteins. The experimental focus is on charge movements in the photoreceptor protein, rhodopsin. The effort reported here has concentrated on characterizing the composition and biochemical properties of surface-bound membrane structures.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 31, 1988
- Accession Number
- ADA204381
Entities
People
- H. G. Smith