Cancer Diagnosis by Laser Spectroscopy

Abstract

Significant progress has been achieved to distinguish between cancerous and normal human breast and lung tissues by laser fluorescence spectroscopy. Several spectroscopic methods, such as pulse and CW laser fluorescence spectra, excitation spectra, and picosecond time resolved kinetics were used to investigate cancer and normal tissues. The origin of the spectroscopic differences between cancerous and normal breast and lung tissues was explored experimentally by chemically-treated normal human tissues. A theoretical model to include self absorption by heme-molecules has been developed to understand the spectroscopic differences between cancerous and normal tissues. The studies of human tissue spectroscopy will lead to new insight into light biospy technique to diagnose cancer. Keywords: Fluorescence; Time-resolved spectra; Excitation spectra; Human tumor tissues; human cells.

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Document Details

Document Type
Technical Report
Publication Date
Jan 18, 1989
Accession Number
ADA205222

Entities

People

  • Asima Pradhan
  • G. C. Tang
  • Jiayu Chen
  • Robert Alfano
  • Wenling Sha

Organizations

  • City College of New York

Tags

Communities of Interest

  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Absorption
  • Classification
  • Excitation
  • Fluorescence
  • Frequency Combs
  • Laser Applications
  • Laser Science
  • Laser Spectroscopy
  • Lasers
  • Molecules
  • New York
  • Nonlinear Optics
  • Optical Properties
  • Picosecond Time
  • Pulsed Lasers
  • Spectra
  • Spectroscopy

Fields of Study

  • Physics

Readers

  • Oncology and Biomarker-Based Cancer Detection.
  • Optical Physics and Photonics.

Technology Areas

  • Directed Energy