A New Perspective in the Etiology, Treatment, Prevention and Prediction of Space Motion Sickness
Abstract
Seven male subjects were given the drug phenytoin (dilantin) in double blind, placebo-controlled crossover experiment. Subjects were rotated in a motion stimulus chair while several of their physiological parameters were measured. Subjects treated with dilantin were found to have a greater tolerance to motion sickness than when they were treated with a placebo. Also, dilantin did not affect the physical performance and cognitive skills of the subjects. The research analyzed heart rate, respiration, gastro-intestinal activity, and brain wave activity. The research found an increase in mean heart rates, mean respiration intake volume, and electrosplanchnogram root mean square voltages during motion sickness. Root mean square voltage of subdelta-delta (.05-1 HZ) electroencephalogram (EEG) activity increased in subjects that were least susceptible to motion sickness while subjects that were highly susceptible to motion sickness had insignificant subdelta-delta EEG activity. Motion sickness models were developed using the Barron Associates' Abductive Reasoning Mechanism (ARM) software. Motion sickness prediction models were developed using the ARM software and linear regression. Keywords: Antiemetics, Theses.
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 01, 1988
- Accession Number
- ADA205660
Entities
People
- Rogelio Morales Jr.
Organizations
- Air Force Institute of Technology