Development and Evaluation of Adeno-HTLV-III Hybrid Virus and Non- Cytopathic HTLV-III Mutant for Vaccine Use

Abstract

Acquired immunodeficiency disease syndrome (AIDS ) was initially recognized as a separate disease in 1981. Results from research groups in France and the United States determined that a previously unknown virus called HIV is the primary aetiological agent of AIDS. Two HIV vaccines, a recombinant Adeno- HIV hybrid virus and a recombinant vaccinia HIV will be tested. The recombinant Adeo-HIV virus is being developed as part of this proposal, we will focus on whether generation and cloning of HIV specific killer T cells could be used to protect humans from AIDS.

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Document Details

Document Type
Technical Report
Publication Date
Oct 28, 1988
Accession Number
ADA205753

Entities

People

  • Martha T. Lubet
  • Sandra K. Dusing

Tags

DTIC Thesaurus Topics

  • Acids
  • Acquired Immune Deficiency Syndrome
  • Antigens
  • Blood
  • Blood Cells
  • Cells
  • Chemistry
  • Diseases And Disorders
  • Hiv Infections
  • Immunity
  • Infection
  • Lymphocytes
  • Molecular Biology
  • Proteins
  • United States
  • Vaccines
  • Viruses

Fields of Study

  • Biology

Readers

  • Immunology
  • Virology (or Medical Virology).

Technology Areas

  • Biotechnology