Mood in Relation to Immunocompetence and Physical Illness
Abstract
The objectives of the study are to examine the degree of association of measures of mood and stress with a broad sample of immunocompetence measures and to examine the types of factors (especially endocrinological ones) that mediate the relation of mood, immunocompetence and physical illness. We selected subjects with a diagnosis of cyclothymic personality disorder. These subjects were evaluated for mood, immune functioning, and physical illness. Each subject is to be evaluated 6 times (2 times each in low, normal, and hypomanic mood). We have now screened 900 students and have 21 who are in the research protocol and have completed at least 1 evaluation. We have also assembled a second group as a comparison with subjects diagnosed as major depression unipolar to be tested for mood, immune function and illness at 3 times: before psychotherapy, at its end, and 6 months later. We have assessed 22 patients at the initial point, 21 at termination, and 19 at the 6-month follow-up. We are engaged in data analysis. Keywords: Immuno-competence, Mood, Stress, Physical illness, Psychophysiology, Psychology, Immunology.
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 16, 1989
- Accession Number
- ADA206014
Entities
People
- John Cacciola
- Lester Luborsky
- Michael Prystowsky
- Paul Crits-christoph
Organizations
- University of Pennsylvania