Cellular and Organizational Responses to Combined Kilohertz and Other Nonionizing Electromagnetic Fields

Abstract

The three elements of the research were designed to examine possible biological and medical effects of exposure to the near-field of Loran-C transmitters that operates in a pulse modulated mode at a carrier frequency of 100 KHz. Neurochemical studies tested the effects of single and repeated in vivo exposure to a simulated Loran-C type waveform on the rat brain biogenic amine and opiate receptor systems. We found AM-PM differences in the levels of amines but no field-related effect was detected. Number and affinity of opiate receptors were also not affected by exposure to the combined electric (3 kV/m rms) and magnetic (48 uT rms) components of this Loran-C Type waveform. Behavioral studies compared the rat's known ability to detect low intensity 60 Hz electric fields (<10 KV/m) with potential detection of Loran-like fields. The data showed that rats trained in an operant conditioning task did not reliably detect the 100 KHz at any field strength used (0 to 9 kV/m). Biochemical studies measured ornithine decarboxylase (ODC) activity in tissue culture cells to monitor membrane signal transduction. Exposure to the Loran-C type waveform at 10mV/cm field strength did not modify basal ODC activity in primary bone cells from mouse calvaria.

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Document Details

Document Type
Technical Report
Publication Date
Apr 12, 1989
Accession Number
ADA207468

Entities

People

  • A. Sheppard
  • C. Cain
  • M. Stell
  • S. Bawin
  • W. R. Adey

Organizations

  • Loma Linda University

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Amines
  • Biochemistry
  • Cell Membrane
  • Cells
  • Chemical Analysis
  • Chemical Synthesis
  • Chemistry
  • Detection
  • Electric Fields
  • Electromagnetic Fields
  • Electromagnetic Radiation
  • Health Services
  • Liquid Chromatography
  • Measurement
  • Medical Personnel
  • Organic Chemistry
  • Systems Biology

Fields of Study

  • Biology

Readers

  • Brain and Cognitive Science; Experimental Psychology; Cognitive Neuroscience
  • Electrical Engineering
  • Neuroscience