Macrocycles Containing Tin
Abstract
The main theme of the project has been the development of macromolecular compounds that contain Lewis acidic tin atoms and the application of these compounds as hosts for the complexation of anions and neutral donors. Synthetic procedures were developed for the production of the macromolecular species. A general approach for the production off macrocycles containing tin atoms was reported in Technical Report 1. Alpha, Omega-Distanna-alkanes were prepared and activated for reaction with a di-Grignard reagent to give macrocyclic compounds containing two or four tin atoms, and the products were purified by preparative reverse phase chromatography. Macrobicyclic skeletons were created by reaction of a macrocycle containing two tin atoms with a di-Grignard reagent. The creation of a Lewis acidic host species was accomplished by selective cleavage of a phenyl group from each tin atom in the macromolecule by reaction with HCL or HBr. Methods for observing and quantifying binding of anions by the Lewis acidic hosts were developed. The most useful method involved Tin 119 NMR spectroscopy. X-ray crystallography was employed to characterize the hosts and complexes. Solid state 119 Sn NMR spectroscopy has also been employed to characterize the free hosts and complexes with anions. Keywords; Macrobicyclic compounds, Anion complexation.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 01, 1989
- Accession Number
- ADA208644
Entities
People
- Martin Newcomb
Organizations
- Texas A&M University