Prevention of Influenza and Other Respiratory Diseases - Laboratory Studies
Abstract
The investigations conducted during the period of this contract, from 1 May 1982 to 30 September 1988, were a continuation of similar studies which began at Lowry Air Force Base in 1952. The overall purpose has been the control of febrile respiratory disease in the Armed Services, particularly in the recruit population at Lowry Air Force Base since the administration of live oral vaccine containing Types 4 and 7. This has been given to recruits soon after arrival at Lackland Air Force Base since 1973. While occasional cases have been detected each winter, the numbers have been so small that the impact of adenovirus disease is no longer considered important by the Air Force. Adenovirus vaccination was discontinued in the fall of 1987. Influenza, however, has continued to occur at the Base with one or another subtype of influenza A or influenza B or both occurring each winter. While the situation has been highly satisfactory for the past few years, questions raised has been highly satisfactory for the past few years, questions raised by antigenic drift and antigenic shift continue to cloud the future. Keywords: Hemagglutinin, Protective antibody level, Antigenic drift, Antigenic shift, Avidity.
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 10, 1989
- Accession Number
- ADA208818
Entities
People
- Gordon Meiklejohn
- Theodore C. Eickhoff
Organizations
- University of Colorado Health