Human Health Studies of Carbon Monoxide (CO) Under Conditions of Military Weapons Systems Crewman Exposures. Protocol 1: Formation of COHb

Abstract

The present experiment was performed as a first step to evaluate the accuracy of prediction of carboxyhemoglobin (COHb) formation due to quasi steady state carbon monoxide (CO) exposure by use of the Coburn-Forster-Kane equation (CFKE) and related models. Thirteen healthy young males were exposed to CO in room air for 120 minutes. While they were being exposed to CO, they either rested or performed bicycle exercise at one of two moderate work levels (25 or 40 Watts). Also during exposure to CO, blood samples were drawn every fine min to assess the COHb level. Many of the variables of the CFKE were measured in individual subjects rather than using published norms. Keywords: Clinical study; Carbon monoxide; Carboxyhemoglobin; Weapons effects; Volunteers; Air pollution.

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Document Details

Document Type
Technical Report
Publication Date
Sep 29, 1988
Accession Number
ADA210344

Entities

People

  • Mathew L. Petrovick
  • Michael L. Mccartney
  • Milan Hazucha
  • Paul N. Kizakevich
  • Vernon A. Benignus

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  • Biomedical

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  • Accuracy
  • Barometric Pressure
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  • Carbon Monoxide
  • Cardiovascular Physiological Phenomena
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  • Differential Equations
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  • Medical Personnel
  • Partial Pressure
  • Plastic Explosives
  • Steady State

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