Synthetic Helizyme Enzymes
Abstract
The goal of this project is to design and synthesize totally new, man-made enzymes. A peptide structure having catalytic activity resembling that of chymotrypsin was designed by computer graphics modelling and synthesized by solid phase peptide synthesis methods. This synthetic peptide, having 72 amino acid residues, has activity to catalyze the hydrolysis of small molecule substrates for chymotrypsin.
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 18, 1989
- Accession Number
- ADA211789
Entities
People
- John M. Stewart
- Karl Hahn
- Wieslaw A. Klis
Organizations
- University of Colorado Health