1H and 13C Nuclear Magnetic Resonance of Dihydroimidazo-Pyridine and Imidazo-(1,2-a)-Pyridine Derivatives.
Abstract
Replacement of the aromatic hydrogens of the pyridinium moiety of the dihydroimidazopyridine and imidazo(1,2-a) -pyridine derivatives with electron-donating and electron-withdrawing substituents causes displacement of the chemical shifts of aromatic protons. Quaternization of the nitrogen atoms causes molecular perturbations and affects the 1H and 13C nuclear magnetic resonance chemical shifts. The sign of the C and C8a displacements can be used to detect the site of quaternization. Dihydroimidazo-pyridines, Imidazo-pyridines, Quaternization effects, Organic chemistry. (jes)
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 1989
- Accession Number
- ADA212713
Entities
People
- August J. Muller
- Everett O. Lewis
- Fu-lian Hsu
- Shekhar Munavalli
- William T. Beaudry
Organizations
- Edgewood Chemical Biological Center