High-Frequency Ventilation in Dogs with Three Gases of Different Densities

Abstract

Dogs were ventilated with a high frequency oscillation, HFO, device varying the frequency (2 - 20 Hz), the tidal volume (25 - 100 ml), and the resident gas (He, N2, SF6)> Tidal volume was measured with a body plethysmograph. Blood gases were measured after a quasi steady state was established. The kinematic viscosity of the breathing gas mixture, which changed by 1700%, was found to have little effect on arterial Po2 and Pco2. The results are consistent with findings in a model which consisted of tubes of different diameters and with the theory of Taylor-type diffusion. In addition, experiments were performed reducing and increasing the equipment dead space. This resulted in changes of P02 and Pc02 that were appreciably less than those resulting from variations of tidal volume of the same magnitude. These results suggest that, high frequency ventilation, HFV, at increased and decreased ambient pressure is technically possible. Keywords: Gas exchange; High frequency ventilation; High frequency oscillations; Augmented diffusion; Deep sea diving; Gas Separation; Breathing devices.

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Document Details

Document Type
Technical Report
Publication Date
Aug 15, 1989
Accession Number
ADA212862

Entities

People

  • Marc L. Jaeger

Organizations

  • University of Florida

Tags

Communities of Interest

  • Biomedical
  • Energy and Power Technologies
  • Engineered Resilient Systems
  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Airway Management
  • Boundary Layer
  • Diffusion
  • Equations
  • Flow Rate
  • Fluid Dynamics
  • Fluid Flow
  • Fluid Mechanics
  • Frequency
  • Geometry
  • Hydrodynamics
  • Laminar Flow
  • Measurement
  • Pipe Flow
  • Pressure Transducers
  • Steady Flow
  • Steady State

Readers

  • Combustion and Flow Dynamics.
  • Combustion science or combustion engineering.
  • Marine Mammal Biology

Technology Areas

  • Space
  • Space - Hall-Effect Thruster