Primary Dermal Irritation Potential of JA-2 Solid Propellant in Rabbits

Abstract

The primary dermal irritation potential of JA-2 Solid Propellant was determined in female New Zealand White rabbits by using a modified Draize method. Very slight erythema and edema were observed in 1 of 8 rabbits one hour after dosing. This rabbit had returned to normal by 24 hours after dosing. No other recognizable skin reaction was detected at any time during the 14-day observation period. The test compound was non-irritating under conditions of this study. Keywords: Toxicity; JA-2 Solid propellant; Primary dermal irritation; Mammalian toxicology; Nitroglycerin; Munitions; Diethyleneglycol dinitrate; Rabbits.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1989
Accession Number
ADA215145

Entities

People

  • Don W. Korte Jr.
  • Earl W. Morgan
  • James D. Justus

Organizations

  • Letterman Army Hospital

Tags

DTIC Thesaurus Topics

  • Biomedical Research
  • Chemical Analysis
  • Health
  • Health Services
  • Irritation
  • Liquid Explosives
  • Materials
  • Materials Laboratories
  • Medical Personnel
  • New Zealand
  • Observation
  • Propellants
  • Rodents
  • Solid Propellants
  • Toxicity
  • Triple Base Propellants
  • United States

Readers

  • Circadian Sleep-Wake Regulation and Chronobiology
  • Toxicology/Environmental Toxicology