Acute Dermal Toxicity of DIGL-RP Solid Propellant in Rabbits
Abstract
The acute dermal toxicity of DIGL-RP Solid Propellant was evaluated in six male and six female New Zealand White rabbits. Moistened ground DIGL-RP (2 g/kg) was applied topically to the clipped dorsal skin surface under a semi- occlusive wrap for 24 hours. No signs of dermal irritation, or systemic toxicity, or death were obtained that could be attributed to DIGL-RP. These data indicate that DIGL-RP Solid Propellant does not produce systemic toxicity when administered by 24-hour topical application at a limit dose of 2 g/kg. (kt)
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 1989
- Accession Number
- ADA215146
Entities
People
- Don W. Korte Jr.
- James D. Justus
- Larry D. Brown
Organizations
- Letterman Army Hospital