A Cepstral Analysis of EEG (Electroencephalographic) Signals in Motion Sickness Studies

Abstract

This research studied electroencephalographic (EEG) signals during the evolution of motion sickness. It used cepstral transformation techniques and hypothesis testing to investigate the relationships between phenytoin serum levels and malaise period EEG signals. It used the same techniques to study the relationships between phenytoin-malaise period EEG signals and placebo-malaise period EEG signals. It also studied the relationships between pre-malaise period EEG signals for phenytoin and placebo trials. Eighteen male subjects were given the drug phenytoin in a double-blind, placebo-controlled crossover experiment. Subjects were rotated in a motion chair while eight physiological parameters were measured. Although the drug delayed or prevented the onset of emesis, no statistically significant relationships were found between phenytoin serum levels and frontal-midline EEG signals. Keywords: Military Theses; Motion Sickness. (KT)

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Document Details

Document Type
Technical Report
Publication Date
Dec 01, 1989
Accession Number
ADA215663

Entities

People

  • Russel B. Smith

Organizations

  • Air Force Institute of Technology

Tags

Communities of Interest

  • Energy and Power Technologies
  • Sensors
  • Space

DTIC Thesaurus Topics

  • Anticonvulsants
  • Computers
  • Data Science
  • Databases
  • Detectors
  • Ear
  • Frequency
  • Health Services
  • Information Science
  • Mathematical Models
  • Medical Personnel
  • Motion Sickness
  • Network Science
  • Reasoning
  • Regression Analysis
  • Side Effects
  • Statistical Analysis

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  • Clinical Trial Research.
  • Neuroscience
  • Toxicology/Environmental Toxicology