Primary Eye Irritation Potential of DIGL-RP Solid Propellant in Rabbits

Abstract

The potential for DIGL-RP Solid Propellant to produce primary eye irritation was evaluated in male New Zealand White rabbits by using a modified Draize method. DIGL-RP produced slight conjunctival vasodilation (indicative of mild inflammation), and slight chemosis of the conjunctival membranes. However, these responses were not sufficiently severe to be classified as a positive response. Therefore, the results indicate that DIGL-RP Solid Propellant is not a primary eye irritant under conditions of this study. Keywords: DIGL-RP Solid Propellant; Diethyleneglycol dinitrate; Mammalian toxicology; Munition; Rabbit.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1989
Accession Number
ADA216138

Entities

People

  • Don W. Korte Jr.
  • Gerald F. Hiatt
  • James D. Justus

Organizations

  • Letterman Army Hospital

Tags

DTIC Thesaurus Topics

  • Animal Structures
  • Biomedical Research
  • Blood Vessels
  • Classification
  • Eye
  • Health Services
  • Irritation
  • Materials
  • Materials Laboratories
  • Medical Personnel
  • Membranes
  • New Zealand
  • Personnel Management
  • Propellants
  • Security
  • Solid Propellants
  • Toxicology

Readers

  • Toxicology/Environmental Toxicology