Advanced Biosensors for Amino Acid Detection. Phase 1

Abstract

Reversible optical detection has been achieved for the amino acids phenylalanine and 3-hydroxytyrosine using chromagenic acyclic polyether host molecules immobilized on a fiber optic substrate. For the hosts investigated tryptophan was found inactive which permitted selective phenylalanine recognition in its presence. Detection was achieved by continuous monitoring of evanescent wave interaction at the fiber optic/chromagenic host interfacial region. Keywords: Amino acids; Biosensors; Fiber optic sensors.

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Document Details

Document Type
Technical Report
Publication Date
Dec 31, 1989
Accession Number
ADA217329

Entities

People

  • A. F. Sammells
  • R. C. Macduff
  • R. L. Cook

Tags

Communities of Interest

  • Advanced Electronics
  • Sensors

DTIC Thesaurus Topics

  • Aluminum Oxides
  • Amines
  • Amino Acids
  • Aqueous Solutions
  • Aromatic Amino Acids
  • Cellulose Acetates
  • Data Acquisition
  • Detection
  • Detectors
  • Evanescent Waves
  • Flow Rate
  • Molecules
  • Optical Detection
  • Optical Detectors
  • Optical Fibers
  • Optical Waveguides
  • Phosphine Oxides

Fields of Study

  • Engineering

Readers

  • Molecular and Cellular Biochemistry
  • Optical Physics and Photonics.

Technology Areas

  • Biotechnology