Lethality Rate Estimation and Testing Procedures

Abstract

Statistical methods were developed for the incorporation of the historical data accumulated on animal studies to enhance the statistical sensitivity of individual comparisons between standards and candidates. The basic idea is that the historical levels and variability of the standard can be used to predict a likely range for the concurrent standard in testing. Keywords: Chemical decontamination; Chemical warfare; Drugs; Statistical methods; Historical comparison; Model fitting; Nonlinear regression analysis; RA V.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Sep 11, 1989
Accession Number
ADA217439

Entities

People

  • Frederick R. Todt
  • Paul I. Feder
  • Ronald L. Joiner
  • Steven W. Rust

Organizations

  • Battelle Memorial Institute

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Analysis Of Variance
  • Body Weight
  • Computer Programs
  • Computers
  • Data Analysis
  • Data Mining
  • Data Science
  • Databases
  • Experimental Design
  • Factor Analysis
  • Information Science
  • Normal Distribution
  • Plastic Explosives
  • Probability
  • Regression Analysis
  • Statistical Analysis
  • Test Methods

Readers

  • Analytical Chemistry
  • Computational Modeling and Simulation
  • Toxicology/Environmental Toxicology