Mechanisms of Microwave Induced Damage in Biologic Materials
Abstract
This research program to elucidate the athermal effects of electromagnetic fields and biological systems has divided along two main focus areas: one involving a primarily physical approach to the problem, the second involving a biological approach. The physical approach has taken the form of 1) dynamical modeling studies that attempt to characterize the interaction mechanism and explore some of its consequences, and 2) microwave, dielectric and optical spectroscopic studies in which the interactions of high frequency fields with DNA molecules are studied. The modeling work included both molecular dynamics simulation studies and phenomenological lines of attack. In the latter, a 'depletion model' has been developed which accounts semiquantitatively for may of the observed features of gene expression alteration by electromagnetic fields. The spectroscopic work--particularly the dielectric relaxation studies-- has yielded significant insights into the dynamics of molecular, ionic, and cellular responses to exogenous fields. RA 3; Microwave; Irradiation; Cell cultures; Deoxyribonucleic acid.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1989
- Accession Number
- ADA217845
Entities
People
- C. J. Montrose
- J. M. Mullins
- Robert K. Mohr
- Robert Meister
- T. A. Litovitz
Organizations
- The Catholic University of America