The Effects of Graded Exercise at Sea Level on Plasma Proenkephalin Peptide F and Catecholamine Responses
Abstract
The purpose of this study was to evaluate the effects of graded treadmill exercise on plasma proenkephalin Peptide F immunoreactivity (ir) and catecholamine responses. Little data exists regarding the sea level responses of plasma Peptide F ir to exercise. Thirty-five healthy male subjects performed a graded exercise test on a motor-driven treadmill at the exercise intensities of 25, 50, 75, and 100% of VO2max. Significant increases above rest were observed for plasma Peptide F ir and norepinephrine at 75% and 100% of VO2max and at 5 min into recovery. Significant increases in plasma epinephrine were observed at 75 and 100% of VO2max. Whole blood lactate significantly increased above resting values at 50, 75 and 100% of the VO2max and at 5 min into recovery. These data demonstrate that exercise increases plasma Peptide F ir levels at sea level. While the exercise response patterns of Peptide F ir are similar to catecholamines and blood lactate responses, no bi-variate relationships were observed. These data show that sea level response patterns to graded exercise are similar to those previously observed at moderate altitude (2200 m). Keywords: Endogenous opioid peptides; Lactate; Epinephrine; Norepinephrine; Aerobic exercise.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1989
- Accession Number
- ADA218195
Entities
People
- Andrew C. Fry
- Joseph E. Dziados
- Katy L. Reynolds
- Scott E. Gordon
- William J. Kraemer
Organizations
- United States Army Research Institute of Environmental Medicine