Role of Protein Methylation in Halobacterium halobium Phototaxis

Abstract

This project is part of an effort to understand the physical chemical basis of sensory and energy transduction by biological membranes using a model system: the bacterial rhodopsins of the archaebacterium H. halobium. Our objective is to gain insight into the mechanism of signaling by the phototaxis receptors sensory rhodopsin I and II (SR-I and SR-II). Methylation of a set of integral membrane proteins is required for taxis adaption in H. halobium and a 94 kd protein has been linked specifically to SR-I. We aim to determine the relationship between this protein and the 25 kd chromophoric polypeptide of SR- I, and the role of methylation in modulation of phototaxis signals. Keywords: Biosensors; Biochemistry.

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Document Details

Document Type
Technical Report
Publication Date
Feb 01, 1990
Accession Number
ADA218412

Entities

People

  • John L. Spudich

Organizations

  • Albert Einstein College of Medicine

Tags

Communities of Interest

  • Energy and Power Technologies

DTIC Thesaurus Topics

  • Absorption
  • Absorption Spectra
  • Archaeal Proteins
  • Biochemistry
  • Chemical Synthesis
  • Chemistry
  • Chromophores
  • Isomerization
  • Liquid Chromatography
  • Membrane Proteins
  • Membranes
  • Methylation
  • New York
  • Photochemical Reactions
  • Pigments
  • Proteins
  • Spectra

Fields of Study

  • Biology
  • Chemistry

Readers

  • Aerospace Research.
  • Breast cancer cell signaling and growth regulation.
  • Molecular Genetics

Technology Areas

  • Biotechnology