Bioluminescence for Detection of Trace Compounds

Abstract

The results of the Phase I investigation have met, and in many areas surpassed, the initial expectations of our proposal. These results include: 1) development of a near market-ready biosensor carcinogen detection system for use as a general screening test; 2) detection of Ethidium Bromide in the 1 microgram/ml (1 ppm) range with a yet-to-be optimized genetically cloned sensor; 3) lyophilization and very successful rehydration of cloned biosensors after 1.5 months of storage; 4) early progress in the development of a mercury sensor, which establishes a methodology for the development of a variety of specific biosensors; 5) development of several light detection systems that include two photodiode based systems, two battery-powered photomultiplier system, and two film techniques. Biosensors, Bioluminescence, Toxic chemicals, Cloned, Carcinogens, Light detector.

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Document Details

Document Type
Technical Report
Publication Date
Mar 08, 1990
Accession Number
ADA219396

Entities

People

  • Reinhardt A. Rosson

Tags

Communities of Interest

  • Energy and Power Technologies
  • Sensors

DTIC Thesaurus Topics

  • Anti-Bacterial Agents
  • Bacteria
  • Bacteriophages
  • Bioluminescence
  • Biosensors
  • Culture Media
  • Detection
  • Detectors
  • Films
  • Freeze Drying
  • Luminescence
  • Materials
  • Microbiology
  • Military Research
  • Optical Detectors
  • Photodiodes
  • Standards

Readers

  • Analytical Chemistry
  • Molecular and Cellular Biochemistry
  • Software Engineering

Technology Areas

  • Biotechnology
  • Biotechnology - Cancer Biotech
  • Directed Energy