Effects of High Altitude Hypoxia on Lung and Chest Wall Function during Exercise
Abstract
We have, more precisely than ever before, defined the mechanical limitations to normal exercise in healthy persons. In most instances in the normal or moderately fit individual, the ventilatory requirement is such that mechanical limitations are barely reached on expiration but not to inspiratory muscles in heavy exercise and fatigue of respiratory muscles is not a factor. The greater the level of physical fitness, the greater the maximum exercise load the greater the probability that mechanical limitation to flow on expiration and to pressure generation by inspiratory muscles on inspiration will be achieved over a substantial part of the tidal breath. This results in an even higher oxygen cost of respiration in these subjects that reach mechanical limitation. On the other hand, it is only in very rare instances that we observed that this mechanical limitation interfered with the provision of sufficient alvelor hyperventilation in these subjects to achieve adequate gas exchange and arterial oxygenation and acid-base regulation. Keywords: Exercise physiology; Breathing; Limitations to exercise; Breathing-mechanics; Respiratory muscles; RA III.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 27, 1990
- Accession Number
- ADA219814
Entities
People
- Jerome A. Dempsey
Organizations
- University of Wisconsin–Madison