Studies of Epstein-Barr Virus Infection and Immunoregulation in Patients with Aids and Aids-Related Disorders

Abstract

Monocytes and monocyte products have been shown to enhance markedly the growth of EBV-infected B cells; patients with AIDS have an increased frequency of EBV-infected B cells in their peripheral blood. The investigators have further shown that activated peripheral blood monocytes secretes beta 2/IL- 6 which promotes the growth of EBV-infected cells but, in general, IL-6 is not produced by EBV infected B cells. (aw)

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Document Details

Document Type
Technical Report
Publication Date
May 21, 1989
Accession Number
ADA220662

Entities

People

  • Giovanna Tosato

Organizations

  • Food and Drug Administration

Tags

DTIC Thesaurus Topics

  • Acquired Immune Deficiency Syndrome
  • Blood
  • Cardiovascular System
  • Cell Line
  • Cells
  • Chemistry
  • Classification
  • Diseases And Disorders
  • Frequency
  • Growth Factors
  • Hiv Infections
  • Infection
  • Lymphocytes
  • Materials
  • Molecular Weight
  • Molecules
  • Wound Infections

Fields of Study

  • Biology
  • Medicine

Readers

  • Immunology