Chemical Preparation Laboratory for IND Candidate Compounds
Abstract
During the reporting period seven compounds were synthesized and submitted to USAMRIID for testing. Most of these compounds were modified nucleosides derived from ribavirin, selenazole and formycin B, together with triazole heterocycles and an organic ester. Compounds which remain under investigation are a large-scale preparation of Ribavirin as well as the exploratory synthesis of dimethyl-ribavirin amidine and prodrug ester. Subject terms: Nucleosides; Triazoles; Heterocycles; Antivirals; RND Candidates; Prep synthesis; RAI.
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 08, 1990
- Accession Number
- ADA221500
Entities
People
- E. M. Schubert