Retinal Derived Growth Factor: A Regulator of Neural Regeneration and Revascularization in Wound Healing

Abstract

Retinal Derived Growth Factor (a heparin binding growth factor that is identical to aFGF (acidic Fibroblast Growth Factor)) stimulates neurite outgrowth in vitro. We have established a model system that will allow us to determine if a gradient of FGF can cause nerve regeneration in vivo and that this regeneration is predominantly due to increased neurite outgrowth by sensory nerves. (kt)

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Document Details

Document Type
Technical Report
Publication Date
Dec 01, 1989
Accession Number
ADA222313

Entities

People

  • John A. Wagner

Organizations

  • Dana–Farber Cancer Institute

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Cells
  • Central Nervous System
  • Classification
  • Collagen
  • Contracts
  • Growth Factors
  • Laboratory Animals
  • Medical Personnel
  • Nerves
  • Nervous System
  • Neurons
  • Peripheral Nervous System
  • Regulators
  • Sciatic Nerve
  • Security
  • Wound Healing

Fields of Study

  • Medicine

Readers

  • Molecular Biology and Genetics
  • Neuroscience
  • Trauma Surgery or Emergency Medicine.