Spectroscopic Observation of Individual sp3-Nitrogen Stereoisomers. Supersonic Jet Studies of 2-Aminobenzyl Alcohol
Abstract
Conformational analysis of the trivalent nitrogen atom is conceptually complicated because of the presence of two dynamic processes, nitrogen inversion and internal rotation about various single bonds. Experimental investigations of this subject are further entangled because these conformational interconversions have very low barriers and are rapid on the time scale of most experimental observations. Evaluation of the sterodynamics of these systems has typically required one of three tricks to slow the inversion and/or rotation rates: use of electronegative substituents, e.g., Nitrogen- Chlorine derivatives; examination of sterically crowded substrates; or presence of acid or hydrogen bonding solvents. We herein report the first observation of spectra of individual isotopomers of a monosubstituted amine RNH1H2 in which H1 and H2 represent diastereotopic hydrogen atoms under slow exchange conditions. (JG)
Document Details
- Document Type
- Technical Report
- Publication Date
- May 13, 1990
- Accession Number
- ADA222335
Entities
People
- Elliot R. Bernstein
- Henry V. Secor
- Hoong-sun Im
- Jeffrey I. Seeman
Organizations
- Colorado State University