Molecular Mechanisms of Electric Field Interactions with Vertebrate Cells

Abstract

The strategy of this program of research on the molecular mechanisms of electric field interactions with vertebrate cells was based on experiments designed to observe directly the effects of applied fields on living vertebrate cells in culture. Two directly observable electric field induced phenomena are focused on: (1) Measurement of changes of the spatial distribution of local changes of transmembrane potential in perpendicular applied electric fields. (2) electrophoresis of cell surface proteins in tangential applied electric fields. To measure the map the local changes of transmembrane potential drops, we developed a high resolution optical imaging procedure.

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Document Details

Document Type
Technical Report
Publication Date
Jun 12, 1990
Accession Number
ADA222999

Entities

People

  • Watt W. Webb

Organizations

  • Cornell University

Tags

Communities of Interest

  • Weapons Technologies

DTIC Thesaurus Topics

  • Cell Membrane
  • Cell Physiology
  • Cells
  • Coefficients
  • Diffusion Coefficient
  • Ear
  • Electric Fields
  • High Resolution
  • Light Scattering
  • Low Density
  • Measurement
  • Membrane Potentials
  • Molecules
  • Proteins
  • Resonant Frequency
  • Spatial Distribution
  • Vibration

Readers

  • Electrical Engineering
  • Fluid Dynamics.
  • Molecular and Cellular Biochemistry