Chemical Modification of the Olfactory Receptor Epithelium of Vertebrate Species

Abstract

This project seeks to develop methodologies for attachment of cell- surface binding sites to solid surfaces using hydrophilic tethers that incorporate reversible linkers. Characterization of Jeffamine copolymers by capillary zone electrophoresis allows the chainlength distribution to be assayed for industrially available hydrophilic tether components. Organic synthesis is used to prepare shorter tether constituents with fluoridolyzable linkages. Keywords: Olfaction, Covalent modification, Organic chemistry, Jeffamine, Hydrophilic tethers, Capillary electrophoresis.

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Document Details

Document Type
Technical Report
Publication Date
Jun 28, 1990
Accession Number
ADA223756

Entities

People

  • Thomas H. Morton

Organizations

  • University of California, Riverside

Tags

Communities of Interest

  • Advanced Electronics
  • Air Platforms

DTIC Thesaurus Topics

  • Alcohols
  • Capillary Electrophoresis
  • Cells
  • Chemical Synthesis
  • Chemistry
  • Detectors
  • Dielectric Polymers
  • Electrophoresis
  • Ethylene Oxide
  • Hydrophilic Properties
  • Mass Spectra
  • Mass Spectrometry
  • Materials
  • Materials Science
  • Mixtures
  • Molecular Weight
  • Organic Chemistry

Fields of Study

  • Chemistry

Readers

  • Molecular and Cellular Biochemistry
  • Polymer Science and Technology
  • Underwater engineering and Marine Technology.

Technology Areas

  • Microelectronics