Prophylactic and Treatment Drugs for Organophosphorus Poisoning
Abstract
The program is directed at the design and synthesis of treatment and prophylactic drugs as potential defenses against organophosphorus poisoning. During the past year, 11 compounds were submitted: one organophosphate; organophosphate; one physostigmine analog; 3-PAM iodide; one perfluoroalkyl alkyl hydroxylamine; one bis(pyridinyl)urea quaternary salt; two 1,3,4- oxadiazolones; one hydroxyimino-3-methylimidazolium salt; one propanesulfonate; and one 4,4-biphenylene-bis(morpholine). Keywords: Organophosphorus poisons, AChE reactivators, Oximes, Hydroxylamines, Carbamates, Synthesis.
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 01, 1990
- Accession Number
- ADA224977
Entities
People
- B. S. Ross
- C. C. Tseng
- C. L. Stevens
- M. T. Budrick
- P. Blumbergs