The 3D Structures of Some Diarrheal Causing Bacterial Toxins

Abstract

The incorporation of data from additional heavy atom derivatives and the inclusion of anomalous dispersion data improved the electron density map markedly. The short alpha helix lying next to a segment of beta sheet resembles strikingly the structural motif in an MHC class I molecule binding site which also is believed to be present in class II molecules. This further reinforces our feeling that SEB map is biologically and biochemically reasonable. Keyword: Biochemistry, Toxins, Enterotoxins, 3D Structure, X-ray, Toxicity, Diffraction, Crystallography.

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Document Details

Document Type
Technical Report
Publication Date
Jan 02, 1990
Accession Number
ADA225205

Entities

People

  • Martin Sax

Organizations

  • Veterans Administration Medical Center

Tags

DTIC Thesaurus Topics

  • Bacterial Toxins
  • Biological Toxins
  • Biomedical Research
  • Cells
  • Crystal Growth
  • Crystal Structure
  • Crystals
  • Detectors
  • Diffraction
  • Electron Density
  • Electrons
  • Figure Of Merit
  • Immune System
  • Lymphocytes
  • Molecules
  • Phase
  • X Rays

Fields of Study

  • Chemistry

Readers

  • Materials Science and Engineering.
  • Microbial Pathology
  • Molecular Genetics

Technology Areas

  • Microelectronics