Hypertonic/Hyperoncotic Resuscitation from Shock: Reduced Volume Requirement and Lower Intracranial Pressure

Abstract

The completed project accomplished the stated goals: To determine the effects on intracranial pressure (ICP) of resuscitation from hemorrhage using conventional volumes of isotonic (SAL) resuscitation solutions in comparison to small volumes of hypertonic 7.2% saline (HS), hyperoncotic 20% hydroxyethylstarch (HES) or the combination of hypertonic 7.2% saline and 20% hydroxyethylstarch (HES/HS). To determine the effects on cerebral blood flow (CBF) of resuscitation from hemorrhage using conventional volumes of isotonic (SAL) resuscitation solutions in comparison to small volumes of hypertonic 7.2% saline (HS), hyperoncotic 20% hydroxyethylstarch (HES), or the combination of hypertonic 7.2% saline and 20% hydroxyethylstarch (HES/HS).

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1989
Accession Number
ADA225207

Entities

People

  • Donald S. Prough

Organizations

  • Wake Forest School of Medicine

Tags

DTIC Thesaurus Topics

  • Arteries
  • Blood
  • Brain Injuries
  • Cardiovascular Diseases
  • Cardiovascular Physiological Phenomena
  • Cerebrovascular Disorders
  • Health Services
  • Hemorrhagic Shock
  • Medical Personnel
  • Veins

Fields of Study

  • Medicine

Readers

  • Cardiovascular Physiology
  • Neurotoxicology