New Electrorelease Systems Based on Microporous Membranes

Abstract

Electrorelease systems have previously been based on electrochemical release of molecules chemically entrapped in polymer membranes. A new type of electrorelease system is described; this system is based on a microporous Al sub 2 0 sub 3 membrane covered with a barrier layer which seals the pores. Electrorelease occurs upon electrochemical dissolution or disruption of the barrier layer, which opens the pores. Two different barrier layers are investigated: silver and Na(+)-form Nafion. The electrorelease rate can be controlled by partially removing the barrier layer or by dividing the barrier layer into several individually-addressable zones. This configuration may also be used as a multi-dose device. Keywords: Drug release, Insulin release.

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Document Details

Document Type
Technical Report
Publication Date
Aug 02, 1990
Accession Number
ADA225315

Entities

People

  • Charles R. Martin
  • Michael J. Tierney

Organizations

  • Colorado State University

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  • Biomedical

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  • Chemistry
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Fields of Study

  • Chemistry

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  • Electrochemical Engineering/ Fuel Cell Technologies
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