Biochemical-Pathway Diversity in Archaebacteria

Abstract

Extreme halophiles such as Halobacterium vallismortis possess a prehenate dehydratase enzyme which is subject to allosteric activation by hydrophobic amino acids. This example of cross-pathway regulation (termed metabolic interlock) is characteristic of much or all of the Gram-positive lineage of eubacteria. We have extended the enzymological base of information to include organisms within the one of the three methanogen orders that is phylogenetically nearest to the Halobacteriales. Within the methanogen order, Methanomicrobiales, Methanohalophilus mahii (a member of the family Methanosarcinaceae) has been selected for in-depth study. The character states of aromatic amino acid biosynthesis have proven to be generally similar: in comparison of the extreme halophiles and the methanogen order studied here, differences were relatively minor, i.e., being of a quantitative nature rather than of a qualitative nature. (JS)

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Aug 30, 1990
Accession Number
ADA226200

Entities

People

  • Roy A. Jensen

Organizations

  • University of Florida

Tags

DTIC Thesaurus Topics

  • Amino Acids
  • Anabolism
  • Archaea
  • Aromatic Amino Acids
  • Bacteria
  • Chemistry
  • Coding
  • Germoplasm
  • Gram-Negative Bacteria
  • Hydrophobic Properties
  • Notation
  • Personality
  • Regulations
  • Security
  • Symbols
  • Tyrosine
  • Universities

Fields of Study

  • Biology

Readers

  • Canine Service Warrior Training Program for Wounded Warriors in the Veterinary Industry, Supported by Donors.
  • Microbial Pathology
  • Molecular and Cellular Biochemistry