Quarterly Report (3rd) for Contract N00014-88-C-0755 (California University)

Abstract

Six donors have been studied using Tc-99m. One unit of blood was drawn from each donor, concentrated to red cells and stored in the blood bank refrigerator for 5 days. The unit was then glycerolized and frozen. When needed, each unit of blood was thawed and deglycerolized. Enough saline-dextrose solution was added to the cells to make a hematocrit of 45% 2%. CPDA-1 solution was then added in a ratio of 63ml. of anticoagulant to 450 ml. of blood. The red cells were then placed in the blood bank refrigerator and stored for 14 days. At the thirteenth day, a sample of blood was removed and analyzed for sterility using the Bactec instrument. The next day, an aliquot of the blood was then removed and 250 uCi. of Tc-99m was added. This labelled blood was injected into the donor, and baseline samples were drawn at 10, 15, 20 and 60 minutes.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 1990
Accession Number
ADA226506

Entities

People

  • Byron A. Myhre

Organizations

  • University of California, Los Angeles

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Anticoagulants
  • Biomedical Research
  • Blood
  • Blood Banks
  • Blood Cells
  • Blood Donors
  • Blood Transfusions
  • Cell Physiological Processes
  • Cells
  • Hematocrit
  • Infusions
  • Physical Examination (Medicine)
  • Survival
  • Tissue Donors
  • Viability

Readers

  • Analytical Chemistry
  • Cardiovascular Physiology