Antibody to the RNA-Dependent DNA Polymerase of HTLV-III: characterization and Clinical Associations

Abstract

Reverse transcriptase activity of the prototypic AIDS virus, HIV-1, was blocked in vitro by IgG derived from certain individuals infected with this retrovirus. A heterogeneous immune response for inhibition of enzyme function occurred. Loss of this inhibitor may be associated with development of clinical disease. Keywords: AIDS, Antibody, Clinical, HTLV-III, Infectious Diseases.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 1988
Accession Number
ADA227404

Entities

People

  • Jeffrey Laurence

Organizations

  • Cornell University

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Abstracts
  • Acquired Immune Deficiency Syndrome
  • Antibodies
  • Blood
  • Cells
  • Chemistry
  • Diseases And Disorders
  • Health Services
  • Hiv Infections
  • Immunoglobulins
  • Infectious Diseases
  • Inhibition
  • Inhibitors
  • Lymphocytes
  • Proteins
  • Sexually Transmitted Diseases
  • Viruses

Fields of Study

  • Biology

Readers

  • Immunology
  • Molecular Genetics