Hemorrhagic Fever with Renal Syndrome (Korean Hemorrhagic Fever).
Abstract
World-wide, about 200,000 people are hospitalized with Hemorrhagic fever with renal syndrome (HFRS) (3 - 10% fatality) each year. The etiologic agents of HFRS are Hantaan, Seoul and Puumala viruses of the genus Hantavirus, family Bunyaviridae. A severe form of HFRS, caused by Hantaan virus, occurs in Asia and eastern parts of Europe, a moderate form, caused by Seoul virus, occurs in Asia, and mild form, caused by Puumala virus, occurs in Europe. The reservoirs of hantaviruses are rodents and other small mammals. Global surveys of the distribution of hantaviruses and surveillance of HFRS are important for prevention of this highly fatal disease. A simple and rapid serologic diagnostic test for HFRS in the areas where hantaviruses exist is urgently needed. It is also important to investigate antigenic differences of strains of Hantavirus isolated from rodents caught in non-endemic areas of the world because HFRS patients have never been documented in many areas despite the finding of positive rodents there. Keywords: Hantavirus, Hantaan, Seoul, Puumala virus, Global survey, Hemorrhagic diseases, High density, Particle agglutination. (js)
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 29, 1990
- Accession Number
- ADA227945
Entities
People
- Ho Wai Howard Lee
Organizations
- Korea University