The Comparison of Gemfibrozil and Lovastatin Therapy in Patients with High LDL and Low HDL Cholesterol Levels

Abstract

Pharmacologic interventions in primary hypercholesteremia are usually considered after saturated fat restricted diet has failed to achieve an adequate control. The specific drug selected may be based, among other things, on its cholesterol lowering efficacy, ability to incidence of coronary heart disease (CHD), long term safety record, and cost. In addition, the individual patient lipoprotein profile and the established agents on specific profile components may be considered. Framingham, MRFIT, and epidemiological studies demonstrated that patients with increased low-density lipoprotein (LDL) cholesterol Clinics Trial showed that lowering elevated levels of LDL cholesterol significantly lowered the risk of CHD development.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 1990
Accession Number
ADA227977

Entities

People

  • Michael D Barnett

Organizations

  • Air Force Institute of Technology

Tags

DTIC Thesaurus Topics

  • Bile
  • Chemical Synthesis
  • Chemistry
  • Drug Abuse
  • Drug Therapy
  • Health Services
  • Internal Medicine
  • Lipids
  • Medical Personnel
  • Pharmacies
  • Side Effects
  • Therapy

Fields of Study

  • Medicine

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