Relationship of Transfusion and Infection in a Burn Population
Abstract
The relationship between the number of red blood cell transfusions and major infections complications was evaluated in 594 thermal injury patients admitted between 1982 and 1986 who had burns over 10% or more of total body surface area and survived more than 10 days. The mean age of this group was 32.9 years, with a mean burn size of 36% of total body surface area; 83% were male. Of the 594 patients, 23.7% died and 38.7% had documented inhalation injury. The mean number of red blood cell transfusion received was 19.7, with a range of 0 to 201. Two hundred fourteen patients (36%) had major infectious complication, defined as pneumonia or invasive burn wound infection. A cross-tabulation of predicted mortality, number of transfusions, and infectious complications revealed a significant positive correlation between transfusion number and infectious complications in patients with predicted mortalities between 10 and 70%. (JS)
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1989
- Accession Number
- ADA228501
Entities
People
- Arthur D. Mason Jr.
- Basil A. Pruitt Jr.
- Theresa A. Graves
- William F. McManus
- William G. Cioffi
Organizations
- United States Army Institute of Surgical Research