Molecular Biology of STLV-III and HTLV-IV

Abstract

Molecular characterization of the SIV mac 251 clone that exhibits in vitro replication competence, but poor in vivo replication ability was initiated by complete nucleotide sequence determination. Defects in the vpr, nef and env genes were noted and will be the focus of future efforts to restore in vivo replication competence of this cloned virus. (js)

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Document Details

Document Type
Technical Report
Publication Date
Aug 10, 1989
Accession Number
ADA228948

Entities

People

  • Joseph Sodroski

Organizations

  • Dana–Farber Cancer Institute

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Amino Acids
  • Availability
  • Biochemistry
  • Biology
  • Cells
  • Chemistry
  • Classification
  • Explosives Initiators
  • Gene Expression
  • Genetic Code
  • Lymphocytes
  • Methionine
  • Molecular Biology
  • Nucleotides
  • Security
  • Sequence Analysis

Fields of Study

  • Biology
  • Chemistry

Readers

  • Immunology
  • Virology (or Medical Virology).