An Analysis of the Effects of Phenytoin in Treating Motion Sickness and the Effects of Motion Sickness on the Human Electroencephalogram

Abstract

This research had two goals: to continue the ongoing research at AFIT to determine the efficacy of the anticonvulsant drug phenytoin in combating the onset and progression of motion sickness; and to note whether or not there is a discernable similarity in the brains of the test subjects to indicate a common point of origin (epicenter) and propagation pattern of the effects of motion sickness in the brain. Eight male DOD personnel were used as subjects to complete twelve trials. Four subjects completed the phenytoin verses placebo double-blind crossover experiment. These four subjects experienced a 99% mean increase in their free-time-to-emesis and a 613% mean increase in their symptom-free-times, with one subject remaining asymptomatic throughout his phenytoin trial. (js)

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Document Details

Document Type
Technical Report
Publication Date
Dec 01, 1990
Accession Number
ADA230423

Entities

People

  • Todd M. Banducci

Organizations

  • Air Force Institute of Technology

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Brain
  • Epilepsy
  • Health Services
  • Medical Personnel
  • Motion Sickness
  • Neurons
  • Psychology
  • Seizures
  • Systems Engineering

Fields of Study

  • Medicine

Readers

  • Brain and Cognitive Science; Experimental Psychology; Cognitive Neuroscience
  • Strategic Security Studies