Molecular Architecture for Reagentless Immunosensors

Abstract

In this project, work focused on three major methodologies to simplify the performance of solid-phase immunoassays: Immobilization of immunoglobulins on solid matrices by maintaining the specific binding activity of the idiotypic sites; separation of bound from free antigen without user's intervention; and signal generation as a quantitative indicator of analyte concentration in samples.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Nov 01, 1990
Accession Number
ADA231092

Entities

People

  • Richard G. Lawton
  • Willfried Schram

Organizations

  • University of Michigan

Tags

Communities of Interest

  • Energy and Power Technologies
  • Human Systems

DTIC Thesaurus Topics

  • Abstracts
  • Antibodies
  • Biosensors
  • Chemical Reactions
  • Detection
  • Detectors
  • Generators
  • Immunoassay
  • Immunoglobulins
  • Immunosensors
  • Military Research
  • Molecules
  • Phase
  • Proteins
  • Signal Generation
  • Signal Generators
  • Solid Phases

Readers

  • Molecular and Cellular Biochemistry
  • Theoretical Analysis.