Behavioral and Physiological Effects of Leukotriene C4

Abstract

The leukotrienes have emerged as an important class of biological mediators, although little information is available regarding their effects on behavioral processes. They have physiological roles in vasoregulation, neurotransmission hormonal regulation, smooth muscle contraction, and may also participate in inflammatory processes, anaphylactic shock and asthma. The peptide leukotrienes are derived from arachidonic acid through the lipoxygenase pathway and consist of leukotrienes (LT) C4, D4, and E4. Some biological activities attributed to LTC4 may be indirect through its conversion to LTD4 or LTE4.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1990
Accession Number
ADA231197

Entities

People

  • H. D. Davis
  • M. R. Landauer
  • T. L. Walden

Organizations

  • Armed Forces Radiobiology Research Institute

Tags

Communities of Interest

  • Advanced Electronics

DTIC Thesaurus Topics

  • Animals
  • Blood
  • Blood Flow
  • Cardiovascular Physiological Phenomena
  • Cardiovascular System
  • Cells
  • Central Nervous System
  • Fatty Acids
  • Ionizing Radiation
  • Nervous System
  • Physiological Effects
  • Radioprotective Agents
  • Rodents
  • Shock (Pathology)
  • Smooth Muscle
  • Stem Cells
  • Therapy

Fields of Study

  • Biology

Readers

  • Immunology and Pathology
  • Molecular and Cellular Biochemistry
  • Neuroscience