Pyridostigmine and Warm Water Diving Protocol 90-05. 1. Protocol and General Results
Abstract
A study was conducted to determine whether pre-treatment with pyridostigmine affected performance of divers in warm water. This report contains a review of pyridostigmine effects, experimental design, and general results obtained from the study. Ten U.S. Navy divers performed two 7-hour warm air/water test exposures. Each test consisted of a 4-hour pre-dive exposure to 37.8 C(100 F) air at the surface, followed by a 3-hour dive in 34.4 C (94 F) water at a depth of 20 fsw (1.6 ATA) breathing 100% O2. Subjects performed light-moderate leg exercise during the immersion phase. During the first 2 h of immersion subjects exercised in a pattern of 30 min work and 10 min rest. During the last hour subjects exercised in a pattern of 5 min light work, 10 min moderate work and 5 min rest. Tests were conducted in a balanced order: once after the subjects ingested pyridostigmine (one 30 mg tablet every 8 h) for two days prior to testing and once after ingesting placebo tablets over the same time periods.
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 01, 1990
- Accession Number
- ADA231430
Entities
People
- A. J. Dutka
- Thomas J. Doubt
Organizations
- Naval Medical Research Center