Modeling of the Laser-Induced Thermal Response, Ablation, and Fragmentation of Biological Tissue

Abstract

This report describes the modeling activities carried out by Physical Sciences Inc. (PSI) during the first year of our ONR Contract N0014-87-C-0161. The objective of this contract is to develop models which can ultimately be used to predict the thermal response, ablation, and fragmentation of hard and soft biological tissue exposed to free electron laser (FEL) radiation. Most of our efforts thus far have been focused on the hard tissue problem, i.e., kidney stones, gallstones, calcified plaque. During this first year of the program modeling efforts have been initiated in four principal areas: (1) further development and application of 1-D and 2-D numerical heat conduction codes to model the thermal damage and ablation of soft tissue exposed to infrared laser energy, (2) modeling of plasma initiation mechanisms in, and resulting plasma spectral emissions from, pulsed laser-irradiated kidney stones and gallstones, (3) modeling of laser-driven shock-induced fragmentation of kidney stones and gallstones, and (4) modeling of the above surface hydrodynamics, i.e., bubble growth and acoustic wave propagation, resulting from plasma-mediated laser energy deposition above a hard tissue surface in a fluid medium.

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Document Details

Document Type
Technical Report
Publication Date
Apr 27, 1988
Accession Number
ADA232046

Entities

People

  • David M. Rosen
  • G. Simons
  • G. Weyl
  • H. Petschek
  • L. Popper

Organizations

  • Physical Sciences (United States)

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Ablation
  • Acoustic Propagation
  • Acoustic Waves
  • Conduction (Heat Transfer)
  • Electrons
  • Fluid Dynamics
  • Fluid Mechanics
  • Free Electron Lasers
  • Laser Beams
  • Lasers
  • Light (Electromagnetic Radiation)
  • Thermal Conductivity
  • Thermal Diffusivity
  • Thermophysical Properties
  • Three Dimensional
  • Two Dimensional
  • Wave Propagation

Fields of Study

  • Physics

Readers

  • Explosive Engineering.
  • Pulsed Power and Plasma Physics.
  • Toxicology/Environmental Toxicology

Technology Areas

  • Directed Energy
  • Microelectronics