Evaluation of Liposome-Encapsulated Hemoglobin/LR16 Formulation as a Potential Blood Substitute

Abstract

During the last four months of our project entitled 'Evaluation of Liposome-Encapsulated Hemoglobin/LR16 Formulation as a Potential Blood Substitute', efforts have been made in the following four areas: (1) the resynthesis of LR16; (2) physical characterization of LEH/LR16 formulations; (3) design and development of membrane-impermeable LR16 analogues; and (4) preparations for small animal testing of surrogate blood preparations. The work completed in each of these areas is outlined below.

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Document Details

Document Type
Technical Report
Publication Date
Mar 15, 1991
Accession Number
ADA233973

Entities

People

  • Thomas G. Burke

Organizations

  • City of Hope National Medical Center

Tags

DTIC Thesaurus Topics

  • Analogs
  • Blood
  • Blood Plasma
  • Blood Substitutes
  • Body Fluids
  • Cells
  • Chemistry
  • Cost Estimates
  • Electric Fields
  • Films
  • Health Services
  • Liquid Chromatography
  • Materials
  • Measurement
  • Military Research
  • Monomolecular Films
  • Synthetic Membranes

Readers

  • Nuclear Civil Defense.
  • Petroleum Engineering
  • Technical Research and Report Writing.