Prophylactic and Treatment Drugs for Organophosphorus Poisoning

Abstract

The program is directed at the design and synthesis of treatment and prophylactic drugs as potential defenses against organophosphorus poisoning. During the past year, 23 compounds were submitted: three organophosphonates, eight carbamates, one organophosphinic acid, two sadium alkylthiosulfonates, thiosulfonates, thiotaurine, and homothiotaurine, cis-4-chlorobuten-1-o1 and 4- chlorobutanol, one alkylaryl disulfide, two chloroalky(aryl) carboxylic acids, 1,3,5-tris-2'-chloroethylbenzene and d8-thiodiglycol.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 1990
Accession Number
ADA234671

Entities

People

  • B. S. Moss
  • C. C. Tseng
  • C. L. Stevens
  • M. T. Budrick
  • P. Blumbergs

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Acids
  • Alcohols
  • Alkanes
  • Alkenes
  • Amines
  • Anhydrides
  • Biomedical Research
  • Carboxylic Acids
  • Chemical Compounds
  • Chlorides
  • Contracts
  • Esters
  • Ethers
  • Hydrogen
  • Organophosphorus Compounds
  • Sodium Compounds
  • Sodium Hydroxide

Fields of Study

  • Chemistry

Readers

  • Neurotoxicology