Fundamental Studies in the Molecular Basis of Laser Induced Retinal Damage

Abstract

The January 1988 issue of Physics Today featured our work on the biophysics of visual photoreception. In this work we investigated the absorption of a single photon by a pigment molecule called rhodopsin in a photoreceptor cell in the retina. The retina is where the excitation of visual sensation begins, where single photons are amplified, where the eye adapts to light levels and generates a partially processed signal to the brain. Except for the partial processing of the image, these functions of the retina occur largely in a cell called the photoreceptor, which absorbs and amplifies the photon and transduces it to a neural response. We also explore the absorption and surface-enhanced Raman spectra of mono-layers of retinal and styryl pyridinium dyes were obtained. The results have yielded new information on the absorption properties of these highly polarizable molecules. Information on the structure of the monolayer films have been deduced from the vibrational spectra.

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Document Details

Document Type
Technical Report
Publication Date
Dec 30, 1989
Accession Number
ADA235682

Entities

People

  • Aaron Lewis

Tags

Communities of Interest

  • Biomedical
  • Energy and Power Technologies

DTIC Thesaurus Topics

  • Absorption
  • Air Force
  • Argon Lasers
  • Chemistry
  • Diffraction
  • Films
  • Laser Beams
  • Liquid Chromatography
  • Materials
  • Materials Science
  • Measurement
  • Molecules
  • Raman Spectra
  • Raman Spectroscopy
  • Scattering
  • Spectra
  • Vibrational Spectra

Fields of Study

  • Physics

Readers

  • Chemistry (specifically Chemical Fluorescence)
  • Neuroscience
  • Optical Physics and Photonics.

Technology Areas

  • Biotechnology
  • Directed Energy
  • Directed Energy - Lasers