Immune Response to Plasmodium Berghei Sporozoite Antigens. I. Evaluation of Murine T Cell Repertoire Following Immunization with Irradiated Sporozoites
Abstract
Information regarding T cell responses to complex antigens found on parasites, like the protozoan Plasmodia, is incomplete and fragmentary. Throughout this study, we were guided by the lessons learned from extensively studied immune responses to soluble protein antigens. The usefulness of this approach should be critically evaluated so that studies dealing with immune reactiveness elicited by antigenically complex parasites could either assume new directions or continue to rely on the models provided by the well characterized protein antigen systems.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1990
- Accession Number
- ADA237184
Entities
People
- Heidi T. Link
- Urszula Krzych
- W. R. Ballou
Organizations
- Walter Reed Army Institute of Research