Vestibular Efferent Activity in Squirrel Monkeys
Abstract
All vertebrates are endowed with a vestibular efferent system (EVS) consisting of somata within the Central Nervous System with long axons exiting the brain to innervate the labyrinth. Behaviorally relevant stimuli related to feeding and/or aggressive behaviors and conditions leading to enhanced attentional states or alerting, activate the EVS. Increased EVS activity modifies the resting rate and response dynamics to motion of vestibular afferents. This modification is non-uniform across the fiber spectrum of the semicircular canals, for example, affecting the more sensitive, low spontaneous activity cells more profoundly than their less sensitive counterparts. The cellular bases for EVS effects are excitatory axo-axonic synapses upon primary afferents and axo-somatic inhibitory synapses upon hair cells.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 1990
- Accession Number
- ADA237286
Entities
People
- Stephen M. Highstein
Organizations
- Washington University in St. Louis